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Improve Patient Adherence.

Keep patients engaged, on track, and following their care plan, from enrollment through recovery and beyond.

HIPAA Compliant
SOC 2 Certified
Care Plan Progress
Jennifer M.
Diabetes Management · Enrolled 32 days ago
3
On Track
1
At Risk
0
Overdue
Education Complete
Week 1
Completed
Lab Results Logged
Week 2
Completed
Medication Check-In
Week 3
Needs Follow-Up
HbA1c Goals Review
Week 4
Upcoming
Care Gap Assessment
Week 6
Upcoming
Adherence Score72%

Adherence Doesn't Fail Because Patients Don't Care.

Patients leave the clinic with good intentions. They want to take their medications, follow the diet, attend follow-ups, and complete their care plan. What patients lack isn't motivation. It's the infrastructure to stay on track. Without structured touchpoints, timely reminders, and educational support that meets them where they are, adherence degrades naturally.

The challenge isn't convincing patients to comply. It's building the systems that keep them informed, reinforced, and supported through every week of their care journey, not just the day of their appointment.

Without those systems, the burden falls entirely on patients to self-manage and on staff to manually chase follow-up. Neither works at scale. And the gap between clinical intent and patient reality widens with every week that passes.

No structured follow-up after discharge
Medication complexity
Health literacy gaps
No behavioral reinforcement
Staff capacity limits
Fragmented care

Non-Adherence Is the Largest Preventable Driver of Poor Outcomes.

The cost of non-adherence extends far beyond missed appointments. It drives complications, hospitalizations, and avoidable spending that compounds across your patient population.

$528 B
Annual Cost of Non-Adherence

Non-adherence to medications costs the U.S. healthcare system an estimated $528 billion per year in avoidable spending, one of the single largest drivers of waste in both fee-for-service and value-based contracts.

NEHI; Ann Intern Med (2012) PMC3262520

50%
Chronic Disease Patients Not Fully Adherent

Only half of patients with chronic conditions take their medications as prescribed, meaning half your highest-cost patients are not receiving the clinical benefit of their treatment plan.

World Health Organization (2003); reaffirmed CDC 2021

25%
Of All U.S. Hospitalizations

Non-adherence can be attributed to up to 25% of hospitalizations in the U.S., a direct driver of readmission rates, CMS penalties, and total cost of care performance.

Duke Health; Ann Intern Med (2012)

125,000
Preventable Deaths Per Year

Non-adherence to prescribed medications contributes to an estimated 125,000 preventable deaths annually, a patient safety emergency at a scale that dwarfs most other addressable causes.

Ann Intern Med; PMC3262520 (2012)

36%
Adults with Low Health Literacy

More than one in three American adults lack the health literacy to reliably understand and act on care instructions. It is the foundational barrier to adherence that no clinical protocol can overcome without deliberate patient engagement design.

NCES; AHRQ Health Literacy Toolkit (2020)

Calculate Your Adherence Impact

See how Subflow can improve adherence rates and clinical outcomes across your patient population.

Calculate Your ROI

From Enrollment to Outcomes. Every Step Guided.

Patient Enrolled
Care Plan Assigned
Education Delivered
Medication Reminders Sent
Forms & PROs Collected
6
Progress Tracked
7
Low Engagement Detected
8
Clinical Escalation
9
Improved Adherence

Subflow delivers a continuous, automated care journey that keeps patients engaged, educated, and on track, while giving clinicians the visibility to intervene when it matters most. Every touchpoint is tracked, every gap is surfaced, and every escalation is handled automatically.

Adherence Alert
Robert T.
Type 2 Diabetes · 42 days post-enrollment
At Risk
Risk Indicators
No response to last 3 check-ins
Medication adherence: 38%
Education module 3 incomplete
Last engagement: 18 days ago
HbA1c goal not yet reviewed
Recommended Actions
1
Send re-engagement message
2
Schedule pharmacist check-in
3
Flag for care manager review

Surface the Patients Who Are Falling Behind, Before It's Too Late.

Most adherence failures are predictable. Patients who haven't responded to check-ins, haven't confirmed medication refills, or haven't completed their education modules are showing you early warning signs, days or weeks before a care gap becomes a clinical crisis.

Subflow continuously monitors every patient's adherence signals and surfaces risk early, so your care team can intervene proactively rather than reactively, and automated outreach can resolve the majority of gaps without staff involvement at all.

  • Continuous adherence scoring across your entire care population
  • Automatic alerts when engagement drops or milestones are missed
  • Identifies medication, education, and behavioral adherence gaps
  • Tiered escalation: automated outreach first, clinical team second
  • Every interaction timestamped and tracked for audit and care planning

Continuous Care. Without the Manual Effort.

Subflow runs the care plan automatically, delivering the right touchpoint, at the right time, for every patient.

Evidence-Based Care Plans

Deploy care plans built on clinical guidelines that automatically adapt based on patient diagnosis, procedure type, and individual risk profile.

Medication Reminders

Deliver structured medication adherence reminders with response tracking, capturing confirmation, questions, and side effect reports automatically.

Adaptive Patient Education

Deliver the right educational content at the right time in plain language, with tracking to know what patients have read, watched, or responded to.

Patient-Reported Outcomes (PROs)

Collect structured PRO data at defined intervals, giving clinicians actionable longitudinal data without manual data entry or phone calls.

Longitudinal Progress Tracking

Track every patient's adherence trajectory over time, giving care teams a longitudinal view to identify patterns and adjust interventions.

Ready to see it live?

See the full adherence automation workflow in a personalized demo built around your patient population.

Schedule a Demo

Better Adherence. Better Outcomes. Measurable Results.

Organizations using Subflow's adherence automation see improvements across clinical, operational, and financial metrics.

90%+
Patient Engagement & Adherence

Patients enrolled in Subflow journeys complete care plan milestones and respond to structured touchpoints at rates that far exceed unengaged populations.

Aggregate: Subflow longitudinal care deployments

99%
Patient Satisfaction Score (NPS)

Patients who feel supported and informed throughout their care journey report exceptional satisfaction and are far more likely to remain engaged long-term.

Powder River Surgery Center

74%
Reduction in Post-Op ED Visits

Structured monitoring and early intervention catches complications before they escalate, reducing avoidable emergency department visits post-procedure.

Longitudinal care case study

Built to Work With the Systems You Already Use

Subflow Health is designed to fit into your existing technology ecosystem, not replace it. Through our partnership with Provision Group, we bring decades of enterprise integration expertise to connect Subflow with your EHR, clinical systems, and broader technology stack.

Epic
ModMed
NextGen
Azure
AWS
Cerner
Greenway Health
Veradigm
Epic
ModMed
NextGen
Azure
AWS
Cerner
Greenway Health
Veradigm
athenahealth
eClinicalWorks
Salesforce
Google Cloud
HubSpot
ChartLogic
Amwell
Teledoc
athenahealth
eClinicalWorks
Salesforce
Google Cloud
HubSpot
ChartLogic
Amwell
Teledoc
Native FHIRHL7REST APIsWebhooksEvent-Driven Architecture

Built for Every Organization Managing Longitudinal Care.

Primary Care Practices

Automate chronic disease management, preventive care reminders, and ongoing patient engagement across your entire panel.

ACOs & Value-Based Care Organizations

Drive adherence at scale across large patient populations to improve quality metrics and reduce total cost of care.

Health Systems

Deploy standardized care plans across service lines and specialties, ensuring consistent, evidence-based post-discharge engagement.

Specialty Practices

Extend care beyond the clinic visit with automated follow-up, medication management, and outcomes tracking between appointments.

FQHCs & Community Health Centers

Address health equity by ensuring every patient, regardless of literacy level or digital access, receives the same quality care support.

Employer Health Programs

Engage employees in chronic condition management and preventive health through automated, personalized care plans.

Ready to Improve
Patient Adherence?

See how Subflow helps healthcare organizations build continuous care relationships that keep patients engaged, adherent, and healthy.

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